Surveillance and management of Echinococcus multilocularis in a wildlife park.
Identifieur interne : 000010 ( Main/Exploration ); précédent : 000009; suivant : 000011Surveillance and management of Echinococcus multilocularis in a wildlife park.
Auteurs : Gérald Umhang [France] ; Jennifer Lahoreau [France] ; Vanessa Hormaz [France] ; Jean-Marc Boucher [France] ; Amandine Guenon [France] ; Damien Montange [France] ; Frédéric Grenouillet [France] ; Franck Boue [France]Source :
- Parasitology international [ 1873-0329 ] ; 2016.
Abstract
The fox tapeworm Echinococcus multilocularis is the causative agent of alveolar echinococcosis, a severe zoonotic disease that may be fatal if untreated. A broad spectrum of mammalian species may be accidentally infected even in captivity. In April 2011, liver lesions due to E. multilocularis were observed during the necropsy of a captive-born nutria (Myocastor coypus) in a French wildlife park, leading to initiation of a study to survey the parasite's presence in the park. A comparable environmental contamination with fox's feces infected by E. multilocularis was reported inside (17.8%) and outside (20.6%) the park. E. multilocularis worms were found in the intestines of three of the five roaming foxes shot in the park. Coprological analyses of potential definitive hosts in captivity (fox, lynx, wildcat, genet, wolf, bear and raccoon) revealed infection in one Eurasian wolf. Voles trapped inside the park also had a high prevalence of 5.3%. After diagnosis of alveolar echinococcosis in a Lemur catta during necropsy, four other cases in L. catta were detected by a combination of ultrasound and serology. These animals were treated twice daily with albendazole. The systematic massive metacestode development and numerous protoscoleces in L. catta confirmed their particular sensitivity to E. multilocularis infection. The autochthonous origin of the infection in all the captive animals infected was genetically confirmed by EmsB microsatellite analysis. Preventive measures were implemented to avoid the presence of roaming foxes, contact with potential definitive hosts and contaminated food sources for potential intermediate hosts.
DOI: 10.1016/j.parint.2016.01.008
PubMed: 26780546
Affiliations:
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Chrono-Environnement UMR 6249 Research Team, CNRS-University of Bourgogne-Franche-Comté, Besançon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>WHO Collaborating Centre for Prevention and Treatment of Human Echinococcosis and National Reference Center for Human Alveolar Echinococcosis, CHRU University Hospital, Besançon, France; Chrono-Environnement UMR 6249 Research Team, CNRS-University of Bourgogne-Franche-Comté, Besançon</wicri:regionArea><placeName><region type="region">Bourgogne-Franche-Comté</region><region type="old region">Franche-Comté</region><settlement type="city">Besançon</settlement></placeName></affiliation></author><author><name sortKey="Boue, Franck" sort="Boue, Franck" uniqKey="Boue F" first="Franck" last="Boue">Franck Boue</name><affiliation wicri:level="1"><nlm:affiliation>ANSES LRFSN, Wildlife Surveillance and Eco-epidemiology Unit, National Reference Laboratory for Echinococcus spp., Malzéville, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>ANSES LRFSN, Wildlife Surveillance and Eco-epidemiology Unit, National Reference Laboratory for Echinococcus spp., Malzéville</wicri:regionArea><wicri:noRegion>Malzéville</wicri:noRegion><wicri:noRegion>Malzéville</wicri:noRegion></affiliation></author></analytic><series><title level="j">Parasitology international</title><idno type="eISSN">1873-0329</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The fox tapeworm Echinococcus multilocularis is the causative agent of alveolar echinococcosis, a severe zoonotic disease that may be fatal if untreated. A broad spectrum of mammalian species may be accidentally infected even in captivity. In April 2011, liver lesions due to E. multilocularis were observed during the necropsy of a captive-born nutria (Myocastor coypus) in a French wildlife park, leading to initiation of a study to survey the parasite's presence in the park. A comparable environmental contamination with fox's feces infected by E. multilocularis was reported inside (17.8%) and outside (20.6%) the park. E. multilocularis worms were found in the intestines of three of the five roaming foxes shot in the park. Coprological analyses of potential definitive hosts in captivity (fox, lynx, wildcat, genet, wolf, bear and raccoon) revealed infection in one Eurasian wolf. Voles trapped inside the park also had a high prevalence of 5.3%. After diagnosis of alveolar echinococcosis in a Lemur catta during necropsy, four other cases in L. catta were detected by a combination of ultrasound and serology. These animals were treated twice daily with albendazole. The systematic massive metacestode development and numerous protoscoleces in L. catta confirmed their particular sensitivity to E. multilocularis infection. The autochthonous origin of the infection in all the captive animals infected was genetically confirmed by EmsB microsatellite analysis. Preventive measures were implemented to avoid the presence of roaming foxes, contact with potential definitive hosts and contaminated food sources for potential intermediate hosts.</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Bourgogne-Franche-Comté</li><li>Franche-Comté</li><li>Pays de la Loire</li></region><settlement><li>Besançon</li><li>Nantes</li></settlement></list><tree><country name="France"><noRegion><name sortKey="Umhang, Gerald" sort="Umhang, Gerald" uniqKey="Umhang G" first="Gérald" last="Umhang">Gérald Umhang</name></noRegion><name sortKey="Boucher, Jean Marc" sort="Boucher, Jean Marc" uniqKey="Boucher J" first="Jean-Marc" last="Boucher">Jean-Marc Boucher</name><name sortKey="Boue, Franck" sort="Boue, Franck" uniqKey="Boue F" first="Franck" last="Boue">Franck Boue</name><name sortKey="Grenouillet, Frederic" sort="Grenouillet, Frederic" uniqKey="Grenouillet F" first="Frédéric" last="Grenouillet">Frédéric Grenouillet</name><name sortKey="Guenon, Amandine" sort="Guenon, Amandine" uniqKey="Guenon A" first="Amandine" last="Guenon">Amandine Guenon</name><name sortKey="Hormaz, Vanessa" sort="Hormaz, Vanessa" uniqKey="Hormaz V" first="Vanessa" last="Hormaz">Vanessa Hormaz</name><name sortKey="Lahoreau, Jennifer" sort="Lahoreau, Jennifer" uniqKey="Lahoreau J" first="Jennifer" last="Lahoreau">Jennifer Lahoreau</name><name sortKey="Montange, Damien" sort="Montange, Damien" uniqKey="Montange D" first="Damien" last="Montange">Damien Montange</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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